Muscle Relaxants and Seniors: What You Should Know About Injury Risk

Muscle relaxants are medicines used to treat pain, tight muscles, or spasms. Common ones include baclofen, tizanidine, and cyclobenzaprine. As a chiropractor, I recommend speaking with your doctor or pharmacist for more details about these medications. Ask them about the study I am discussing below.

A study released in September 2025 followed nearly 90,000 people and examined safe muscle relaxants are for older adults (age 65 and up).

Here’s what they found:

Key Findings

  • Baclofen and tizanidine were linked with a higher risk of injury in seniors compared to cyclobenzaprine.

  • Injuries included falls, broken bones, head injuries, and dislocations.

  • The risk was especially high for falls that led to fractures.

  • People who already had health issues like balance problems, Parkinson’s disease, kidney trouble, or who were taking antidepressants faced even higher risks.

Why This Matters

Cyclobenzaprine is already known to be risky for older adults, and doctors are generally advised to avoid it. This new research shows that baclofen and tizanidine may not be safer options — they can actually increase the chance of serious injury.

What Seniors and Caregivers Can Do

  • Ask if you really need a muscle relaxant. Sometimes other treatments like gentle stretching, manual therapy, heat/ice, or exercise can help without the risks.

  • Review your medications. Make sure your doctor/pharmacist knows everything you take — some medicines can add to the risk of falls and drowsiness.

  • If you must use these medicines:

    • Use the lowest dose possible. Again, talk to your pharmacist about dose.

    • Ask if an alternative is available.

    • Take them for the shortest amount of time. The shorter the better.

    • Be extra careful with balance and walking. Slow down, often rushing can cause falls.

  • Talk to your healthcare provider about safer options if you’re concerned.

  • See your chiropractor. As MSK specialists, they can offer drug-free options for the treatment of pain.

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References:

M. M. George, R. L. Deamer, S. Lee-Rodriguez, et al., “ Safety of Baclofen and Tizanidine in Older Adults: A Retrospective Cohort Study in a Large Integrated Health Care System,” Journal of the American Geriatrics Society (2025): 1–9,